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Corbett, K
Shaw, T.K., Paul, P
Nrf 2-regulated glutathione recycling independent of biosynthesis is critical for cell survival during oxidative stress
But quality matters
The triple therapy arm (prednisone + azathioprine + NAC 600 mg three times daily) was stopped early due to increased harm
In the CNS, GSH is synthesized primarily by astrocytes and transported to neurons, where it provides oxidative resistance (Dringen and Arend, 2025)
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